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Anthony (Tony) T. Dren, PhD, RPh

Consulting Professor in the School of Nursing
Email: 
tony.dren@duke.edu
Phone: 
(919) 668-5107
Office: 
Pratt Street, Room 120

Dr. Dren received his doctorate in Pharmacology from the University of Michigan (Ann Arbor) and a Master’s in Pharmacy from Duquesne University (Pittsburgh, PA). He is a registered pharmacist with over 30 years of experience in pre-clinical and clinical drug development with expertise in the design, execution, monitoring and reporting of Phase I-IV multi-center clinical trials. He has held managerial and research positions at Abbott Laboratories, Burroughs Wellcome Co., and, most recently, at Cato Research Ltd. He has implemented, managed, monitored, and reported on more than 40 drug development clinical trials, is credited with the publication of many scientific articles in professional journals, and holds ten patents.

Academic Program Affiliations

  • Master of Science in Nursing Program
  • Doctor of Nursing Practice Program

Education

  • PhD - University of Michigan at Ann Arbor
  • MS - Duquesne University

Research Interests

Design and execution of drug development clinical research studies.

Awards and Honors

  • 2010 || Achievement Award and Alumni Commendation, Duquesne University Tamburitzans
  • 2010 || American Epilepsy Society Fiftieth Anniversary Special Friend Award, American Epilepsy Society
  • 2010 || Central Pharmaceutical Journal Award in Pharmaceutical Administration, Central Pharmaceutical Journal
  • 2010 || Century Club Distinguished Alumnus Award, Duquesne University
  • 1966 || Inducted, Rho Chi
  • 1966 || Inducted, Phi Delta Chi
  • 1961 || NIH Predoctoral Fellow, University of Michigan, United States Public Health Service
  • 1960 || Performing Arts Scholarship, Duquesne University Tamburitzans
  • 1960 || Student Government Achievement Award, Duquesne University
  • 1960 || Student Hall of Fame, Duquesne University

Areas of Expertise

  • Clinical Research Management
  • Pharmacology

Representative Publications

  • 2003 -- Dren, A. T. and Gussin, R. Z. and Diamond, J. and DuCharme, D. W. and Gibb, J. W. and Levin, J. A. and Zedeck, M. S. Memoirs of the early 1960s - The magnificent years. In Sixty-One Years of Michigan Pharmacology 1942-2003 edited by E. F. Domino. 2003; pp. 225-229. : NPP Books. 2003 225-229
  • 2000 -- Dren, A. T. and Turner, G. H. The drug development process: Challenges, changes and careers. Part I. Advance for Nurses. 2000 2(20); 20-22
  • 2000 -- Dren, A. T. and Turner, G. H. The drug development process: Challenges, changes and careers. Part II. Advance for Nurses. 2000 2(21); 18-28
  • 1996 -- PubMed # : 8823232 Anderson, G. D. and Yau, M. K. and Gidal, B. E. and Harris, S. J. and Levy, R. H. and Lai, A. A. and Wolf, K. B. and Wargin, W. A. and Dren, A. T. Bidirectional interaction of valproate and lamotrigine in healthy subjects. Clin Pharmacol Ther. August, 1996 60(2); 145-56
  • 1995 -- Risner, M. E. and Womble, G. P. and Dren, A. T. and Manasco, P. K. Long-term clinical trial experience with Lamictal (lamotrigine) treatment of epilepsy. Epilepsia. 1995 36(Suppl 4); 66
  • 1994 -- Bergen, D. and Ristanovic, R. and Rudd, D. and Dren, A. T. and Klein, K. Placebo-controlled evaluation of clinical laboratory data and body weight during administration of Lamictal in outpatients with partial seizures Epilepsia. 1994 35(Suppl 8); 1963
  • 1993 -- PubMed # : 8232944 Matsuo, F. and Bergen, D. and Faught, E. and Messenheimer, J. A. and Dren, A. T. and Rudd, G. D. and Lineberry, C. G. Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures. U.S. Lamotrigine Protocol 0.5 Clinical Trial Group. Neurology. November, 1993 43(11); 2284-91
  • 1992 -- Dren, A. T. and Risner, M. E. and Womble, G. P. and Yau, M. K. and Rudd, G. D. and Lineberry, C. G. Placebo-controlled add-on experience demonstrating the safety and efficacy of lamotrigine in patients with refractory partial seizures. Journal of Clinical Pharmacology. 1992 32 766
  • 1992 -- Rudd, G. D. and Dren, A. T. and Womble, G. P. and Risner, M. E. and Lineberry, C. G. Comparison of crossover and parallel designs in the clinical evaluation of lamotrigine Pharmacotherapy. 1992 12 263
  • 1991 -- PubMed # : 1681560 Borison, R. L. and Diamond, B. I. and Dren, A. T. Does sigma receptor antagonism predict clinical antipsychotic efficacy? Psychopharmacol Bull. 1991 27(2); 103-6

Pages

Grant Funding (Selected)

  • Clinical Research Management Program for Nurses

    Health Resources and Service Administration (HRSA)
    D09HP07350-02
    07/2006 to 06/2009
    Role: Faculty

    The purpose of this project is to “prepare advanced practice nurses through the enhancement of advanced nursing education and practice".
    The major goal of this project is to develop interactive case scenarios for on-line teaching.