Isaac M. Lipkus, PhD

Professor
Phone: 
(919) 668-2348
Office: 
3067 Pearson Building

Dr. Lipkus is Professor in the School of Nursing and the Department of Community Medicine and Director of the Risk Communication Laboratory. He received his Ph.D. at the University of North Carolina-Chapel Hill, specializing in the area of social psychology. Dr. Lipkus, a nationally and internationally known expert on risk communication, is engaged in development of more effective tools for this purpose. For the last 14 years, his research has focused on cancer prevention and detection, and on the role of risk communication in patients' decisions pertaining to cancer treatment and modification of health behaviors. He has applied social cognitive models (with an emphasis on risk communication processes) to motivate changes in life style such as smoking cessation and changes in diet and exercise; to increase participation in screening for breast cancer and colorectal cancer; and to improve breast cancer treatment decisions. His recent research explores the influence of feedback about genetic factors on decision making concerning smoking cessation and choice of treatment of breast cancer.

Academic Program Affiliations

  • Master of Science in Nursing Program
  • PhD in Nursing Program
  • Doctor of Nursing Practice Program

Education

  • PhD - University of North Carolina - Chapel Hill
  • MA - University of North Carolina - Chapel Hill
  • BS - University of California-San Diego

Research Interests

Dr. Lipkus is interested in:


1) the impact of risk perceptions (e.g., optimistic and pessimistic biases) on modifying precautionary behaviors (e.g., early prevention and detection of cancer, etc.) and

2) how dispositional variables (e.g., hostility) and attitudinal variables (e.g belief in a just world) affect coping with negative life events (e.g., cancer, conflict in interpersonal relationships)

Awards and Honors

  • 1994 || New Directions Award, Academy of Management
  • 1993 || Postdoctoral Felllow in Behavioral Medicine, Department of Psychiatry, Ohio State University
  • 1993 || Postdoctoral Felllow in Psychoneuroimmunology, Ohio State University
  • 1992 || Reuben Hill Award, National Council on Family Relations
  • 1991 || Postdoctoral Fellow, Department of Psychiatry, Duke University Medical Center
  • 1986 || B.S. cum laude (Sociology), University of California - San Diego

Areas of Expertise

  • Oncology
  • Psychiatric / Behavioral Health

Representative Publications

  • 2013 -- PubMed # : 22888806 Shepperd, J. A. and Lipkus, I. M. and Sanderson, S. C. and McBride, C. M. and O'Neill, S. C. and Docherty, S. Testing Different Communication Formats on Responses to Imagined Risk of Having Versus Missing the GSTM1 Gene. J Health Commun. January, 2013 18(1); 124-37 PMC3543503
  • 2012 -- Ranby, K. W. and Lewis, M. A. and Toll, B. A. and Rohrbaugh, M. J. and Lipkus, I. M. Perceptions of smoking related risk and worry among dual-smoker couples. Nicotine and Tobacco Research. September 2012, Epub ahead of print]
  • 2012 -- PubMed # : 22990222 Ranby, K. W. and Lewis, M. A. and Toll, B. A. and Rohrbaugh, M. J. and Lipkus, I. M. Perceptions of Smoking Related Risk and Worry Among Dual-Smoker Couples. Nicotine Tob Res. September, 2012, Epub ahead of print
  • 2012 -- PubMed # : 22927848 Malo, T. L. and Lipkus, I. and Wilson, T. and Han, H. S. and Acs, G. and Vadaparampil, S. T. Treatment Choices Based on OncotypeDx in the Breast Oncology Care Setting. J Cancer Epidemiol. August, 2012 2012 941495 PMC3425834
  • 2012 -- PubMed # : 22283474 Haga, S. S. and O'Daniel, J. M. and Tindall, G. M. and Mills, R. and Lipkus, I. M. and Agans, R. Survey of genetic counselors and clinical geneticists' use and attitudes toward pharmacogenetic testing. Clin Genet. August, 2012 82(2); 115-20 PMC3351546
  • 2012 -- PubMed # : 21633294 Haga, S. B. and O'Daniel, J. M. and Tindall, G. M. and Lipkus, I. R. and Agans, R. Public attitudes toward ancillary information revealed by pharmacogenetic testing under limited information conditions. Genet Med. August, 2012 13(8); 723-8 PMC3150617
  • 2012 -- Haga, S. and O'Daniel, J. and Tindall, G. and Mills, R. and Lipkus, I. and Agans, R. Response to Newman et al. Clin Genet. August, 2012 82(2); 203
  • 2012 -- PubMed # : 22744911 O'Neill, S. C. and Lipkus, I. M. and Sanderson, S. C. and Shepperd, J. and Docherty, S. and McBride, C. M. Motivations for genetic testing for lung cancer risk among young smokers. Tob Control. June 2012, Epub ahead of print
  • 2012 -- PubMed # : 22544562 Mosher, C. E. and Lipkus, I. and Sloane, R. and Snyder, D. C. and Lobach, D. F. and Demark-Wahnefried, W. Long-term outcomes of the FRESH START trial: exploring the role of self-efficacy in cancer survivors' maintenance of dietary practices and physical activity. Psychooncology. April, 2012, Epub ahead of print
  • 2012 -- PubMed # : 22100301 Crockett, S. D. and Lipkus, I. M. and Bright, S. D. and Sampliner, R. E. and Wang, K. K. and Boolchand, V. and Lutzke, L. S. and Shaheen, N. J. Overutilization of endoscopic surveillance in nondysplastic Barrett's esophagus: a multicenter study. Gastrointest Endosc. January, 2012 75(1); 23-31.e2

Pages

Grant Funding (Selected)

  • Effects of Message Framing on Cessation among Couples where both Partners Smoke

    National Institutes of Health
    1R21-CA165194-01A1
    03/2012 to 02/2014
    Role: Principal Investigator

    Project Goal: This study aims to test whether focusing the positive effects of quitting at the level of the individual or couples or the negative effects of continuing to smoke at the level of the individual or couples, influence processes of communal coping and downstream smoking-related outcomes.

  • Preliminary Test of Habit Formation Intervention for Physical Activity in Breast Cancer Survivors

    Duke University School of Nursing Small Grant Project
    09/2012 to 08/2013
    Role: Principal Investigator
  • Motivating Weight Loss in Dual Overweight/Obese Couples

    Duke Cancer Prevention, Detection, and Control Research Program Cancer Control Pilot Award
    07/2012 to 06/2013
    Role: Principal Investigator

    Project goal: To motivate weight loss in obese couples using mental contrasting and implementation intentions.

  • Assessing Risk Communication Educational Practices in Genetic Counseling Programs

    National Institutes of Health
    1R01-HG004322-01A1
    08/2008 to 05/2011
    Role: PI
  • Cancer Information Service

    NIH/NCI (HHSN261200511)
    N02 C0 51105
    01/2005 to 01/2010
    Role: PI

    To support the infrastructure, partnerships and research of the nationally recognized Cancer Information Service.

  • Patient self-management and gene guided therapy for CHC

    National Institutes of Health
    1R21-NR013461-01
    04/2012 to 03/2014
    Role: Co-investigator

    This 2 year exploratory mixed-methods longitudinal case study (n=18) will describe patients’ and providers’ explanations of how and why they engage in technical work (T-WORK) and adaptive work (A-WORK), and adaptive leadership (A-LEAD) and how these strategies promote or pose barriers to patients’ SM in the context of the new genetic marker and treatments.

  • Young Smokers’ Reactions to Genetic Risk for Lung Cancer

    NIH/NCI
    R01 CA121922
    08/2007 to 07/2011
    Role: PI

    The goal of this study understand college smokers’ cognitive and emotional responses to genetic susceptibility feedback and their influence on downstream perceptions of lung cancer risks and worry and initial steps towards cessation.

  • The Effects of Providing Breast Cancer Recurrence using Oncotype Risk

    The Anthony Marchione Foundation
    05/2008 to 12/2009
    Role: PI

    This study aims to explore 1) patients’ accuracy of stating their recurrence risk based on the oncotype DX, 2) how perceptions of recurrence risk affect weighting of treatment risks and benefits and treatment selection, and 3) how numeracy affects process

  • Clinical Validity and Utility of Genomic Targeted Chemoprevention of PCa

    Wake Forest University Health Sciences
    WFUHS-66670
    09/2009 to 08/2010
    Role: PI

    This pilot study explores interest among smokers to test for their risk of developing lung cancer based on epigenetic changes associated with methylation of the p16 protein.

  • Increasing Attention to Smoking Risk Messages

    NIH/NCI
    R01-CA114389
    09/2007 to 07/2009
    Role: PI

    The purpose of this study is to assess the relationship between smokers’ perceptions of risk and motivations to seek out and process information about risks and cessation.

Pages

Faculty News

Lipkus Submits NIH R21 Proposal to Study Impact of Graphic Warning Labels on Smoking

2012-10-21
Isaac Lipkus and team submitted an NIH R21 application entitled "Effects of 3D vs 2D Graphic Warning Labels on Smoking Beliefs and Behaviors" requesting funding for a two-year period with a start...

Lipkus Receives Cancer Control Pilot Award

2012-07-08
Professor Isaac Lipkus received an award for his Cancer Control Pilot Award through the Duke Cancer Prevention, Detection, and Control Research Program for a one-year period, July 1, 2012, to June 30...

DUSON Delegation Travels to China for Scholarly Exchanges, Collaborations in Education and Research

2012-06-03
A delegation of faculty from Duke University School of Nursing (DUSON) will travel to China June 5-15 to participate in scholarly and cultural exchanges and to explore opportunities for educational...

Lipkus Receives $240,690 Grant for Smoking Cessation Program

2012-03-18
Professor Isaac Lipkus received an award for his NIH R21 proposal entitled "Effects of Message Framing on Cessation among Couples Where Both Partners Smoke." The award is for a two-year period, March...

Duke University School of Nursing Co-sponsors International Nursing Conference

2012-02-03
Duke University School of Nursing is co-sponsoring the 2012 Beijing International Nursing Conference, June 7-10, 2012, in Beijing, China. The theme of the conference is “Altogether for Nursing,...