Marilyn J. Hockenberry, PhD, RN, PNP-BC, FAAN

Professor
Phone: 
(919) 684-9330
Office: 
3057 Pearson Building

Dr. Marilyn Hockenberry, PhD, RN, PNP-BC, FAAN, is Professor at the Duke University School of Nursing. Dr. Hockenberry, a distinguished leader in pediatric oncology and evidence-based practices and outcomes, is actively involved in the School’s cancer-related research initiatives and teaches in the DNP program. She also serves as one of the 11 chairs of the Duke Institutional Review Board.

Before coming to Duke, she was Professor of Pediatrics in the Hematology/Oncology Division at Baylor College of Medicine. She also served as the nurse scientist for the hospital and director of the pediatric nurse practitioner program in the Texas Children’s Cancer Center at Texas Children’s Hospital (TCH) from 1994 to 2012. At TCH, she served as director of the Center for Research and Evidence-based Practice from 2002 to 2009 and director of the Evidence-based Outcomes Center from 2004 to 2009. Earlier in her career, she practiced as a hematology/oncology nurse practitioner at Duke University Medical Center and was a clinical associate in the Duke School of Nursing.

Dr. Hockenberry received her BSN from Capital University in Columbus, Ohio, the Master of Science degree from Texas Woman’s University in Houston and her Pediatric Nurse Practitioner certification through Children’s Hospital in Philadelphia. She earned a PhD in nursing with distinction from the Medical College of Georgia. Her research focuses on treatment-related side effects experienced by children who have cancer and is the recipient of numerous research grant awards. Her latest NIH funded research grant evaluates phenotypic and genotypic characteristics and their associations with symptom clusters experienced during treatment for childhood leukemia. She has authored more than 80 publications, and has served for the past 10 years as senior editor for the Wong Pediatric Nursing Textbooks published by Elsevier. She is a Fellow of the American Academy of Nursing. She was appointed as a member of the Children’s Oncology Group Scientific Council in February 2011. She received the 2011 Distinguished Nurse Researcher Award and the 2011 Journal of Pediatric Oncology Nursing Writing Award at the 35th national conference of the Association of Pediatric Hematology/Oncology Nurses.

Academic Program Affiliations

  • PhD in Nursing Program
  • Doctor of Nursing Practice Program

Education

  • PhD - Medical College of Georgia
  • MS - Texas Woman’s University
  • BSN - Capital University

Research Interests

• Symptom assessment in children with cancer
• Physiologic markers and symptom severity
• Academic and cognitive changes in children with leukemia
• Oxidative stress and CNS tissue injury in children with leukemia

Awards and Honors

  • 2011 || Distinguished Researcher Award, National Association of Pediatric Hematology Oncology Nurses (APHON)
  • 2011 || Nursing Discipline-Service Award, Children's Oncology Group
  • 2011 || Writing Award, National Association of Pediatric Hematology Oncology Nurses (APHON)
  • 2006 || Best Nurse Leader Award, Advance for Nurses
  • 2003 || Chapter Friend Award, Houston Area NAPNAP Chapter
  • 1999 || Olivia Hodson Fellowship, Great Ormond Street Hospital for Children, London, Englan d
  • 1998 || APON Bard Access Research Paper, 2nd place, National Association of Pediatric Oncology Nurses
  • 1996 || Oncology Nursing Fellowship (ONF) / Ortho Biotech Clinical Research Scholar, 1996-1998
  • 1995 || Nursing Celebration Honoree, Texas Nurses' Association, District 5
  • 1994 || Oncology Nursing Society (ONS) / Upjohn Quality of Life Award, Oncology Nursing Society
  • 1992 || Fellow, American Academy of Nursing
  • 1991 || NCI-ONS Student Research Award, "Vulnerability to Stress Experienced During Treatment for Childhood Cancer", NCI-ONS
  • 1990 || Inducted, Sigma Theta Tau Nursing Honor Society, Alpha Epsilon Chapter
  • 1990 || Jean Fergusson Excellence in Pediatric Oncology Education Award, Association of Pediatric Oncology Nurses
  • 1990 || Pre Doctoral Research Fellowship, 1990-1992, NIH, National Center for Nursing Research
  • 1989 || Pre Doctoral Research Award, 1989-1992, American Cancer Society
  • 1985 || Oncology Nursing Society/Schering Excellence in Cancer Nursing Research Award, Oncology Nursing Society
  • 1984 || NCI-ONS Student Research Award, "Behavioral Treatment for Children Undergoing Intrusive Procedures", Oncology Nursing Congress, Toronto, CA

Areas of Expertise

  • Oncology
  • Pediatric Nursing

Areas of Interest

Pediatric oncology
Evidence-based practice

Representative Publications

  • 2013 -- PubMed # : 23108342 Rodgers, C. C. and Hooke, M. C. and Hockenberry, M. J. Symptom clusters in children. Curr Opin Support Palliat Care. March, 2013 7(1); 67-72
  • 2013 -- PubMed # : 22856670 Krull, K. R. and Hockenberry, M. J. and Miketova, P. and Carey, M. and Moore, I. M. Chemotherapy-related changes in central nervous system phospholipids and neurocognitive function in childhood acute lymphoblastic leukemia. Leuk Lymphoma. March, 2013 54(3); 535-540
  • 2012 -- Hockenberry, M. J. and Wilson, D. Wong's Essentials of Pediatric Nursing October, 2012
  • 2012 -- PubMed # : 22797682 Mazur, K. A. and McCarthy, K. and Suell, M. N. and Hockenberry, M. J. An outpatient urgent care bay within a pediatric cancer and hematology center. J Pediatr Oncol Nurs. July, 2012 29(4); 206-10
  • 2012 -- PubMed # : 22367765 Hockenberry, M. J. and McCarthy, K. S. and Taylor, O. A. and Hesselgrave, J. and Bernhardt, M. B. and Daves, M. and Kamdar, K. Using improvement science to promote evidence-based practice in a childhood cancer and hematology center. J Pediatr Oncol Nurs. May, 2012 29(1); 5-13
  • 2012 -- PubMed # : 22374494 Rodgers, C. and Norville, R. and Taylor, O. and Poon, C. and Hesselgrave, J. and Gregurich, M. A. and Hockenberry, M. Children's coping strategies for chemotherapy-induced nausea and vomiting. Oncol Nurs Forum. March, 2012 39(2); 202-9
  • 2012 -- PubMed # : 22415856 Rodgers, C. and Gregurich, M. A. and Hockenberry, M. Lipid profiles of pediatric hematopoietic stem cell transplant survivors. J Pediatr Oncol Nurs. March, 2012 29(2); 63-9
  • 2012 -- Hockenberry, M. J. and Rodgers, C. Cancer in children. In Encyclopedia of Nursing Research edited by Fitzpatrick, J. J. & Kazer, M.. 2012; : Springer. 2012
  • 2011 -- PubMed # : 21938763 Moore Ki, I. M. and Hockenberry, M. J. and Anhalt, C. and McCarthy, K. and Krull, K. R. Mathematics intervention for prevention of neurocognitive deficits in childhood leukemia. Pediatr Blood Cancer. September, 2011 PMC3246526
  • 2011 -- PubMed # : 21844243 Mandrell, B. N. and Yang, J. and Hooke, M. C. and Wang, C. and Gattuso, J. S. and Hockenberry, M. and Jones, H. and Zupanec, S. and Hinds, P. S. Psychometric and clinical assessment of the 13-item reduced version of the fatigue scale-adolescent instrument. J Pediatr Oncol Nurs. 28(5); 287-94

Pages

Grant Funding (Selected)

  • Phenotype-Genotype Associations with Symptoms During Childhood Leukemia Treatment

    National Institutes of Health
    1R01-CA169398-01
    09/2012 to 07/2017

    Project Goal: To examine biologic mechanisms that influence symptom toxicities caused by increased oxidative stress or cytokine production or actual failure of the anti-oxidant and anti-inflammatory defense systems due to genetic variation.

  • Program to Integrate Translation Science in Pediatric Oncology Nursing

    Alex's Lemonade Stand
    01/2013 to 12/2013

    The purpose of this project is to provide mentorship for the development of pediatric oncology nursing evidence-based guidelines for the Children’s Oncology Group and the National Association of Pediatric Hematology/Oncology Nurses.

  • The leukemia physical functioning study: longitudinal assessment of peripheral neuropathy and motor function in children treated for average risk acute lymphoblastic leukemia

    National Cancer Institute, Biomarker, Imaging, and Quality of Life Studies Funding Program (BIQSFP)
    07/2011 to 06/2016
    Role: Co-Investigator

    Project Goal: To characterize the onset, severity, and natural history of vincristine-associated
    neuropathy by physical therapists in children undergoing therapy for leukemia.

  • Childhood leukemia: Oxidative stress, cognitive changes & academic outcomes

    NIH-NINR (Subcontract with University of Arizona)
    1R01 NR010889-01A1
    07/2009 to 06/2013
    Role: Co-Investigator

    Project Goal: To investigate relationships among oxidative stress, working memory, motor and visual-motor skills, and academic abilities among children with acute lymphoblastic leukemia (ALL) who are receiving intensive central nervous system (CNS) treatment with methotrexate.

  • Fatigue and carnitine levels in children and adolescents over eight cycles of chemotherapy

    Alex's Lemonade Stand
    07/2008 to 06/2011
    Role: Principal Investigator

    Project Goal: To explore carnitine as a physiologic marker for fatigue in 60 children and adolescents with cancer.

  • Outcome measures for pediatric procedural pain

    Association of Critical Care Nurses
    07/2006 to 06/2007
    Role: Co-PI

    Project Goal: Examine outcome measures for pediatric procedural pain.

  • Symptom clusters in children/teens on cisplatin or ifosfamide

    Oncology Nursing Society, ONS Foundation/CLIR Symptom Cluster Grant
    07/2004 to 06/2006
    Role: Principal Investigator

    Project Goal: Examine symptom clusters in children and adolescents being treated with cisplatin or ifosfamide

  • Enhancing care for children with cancer throughout Texas

    Texas Cancer Council
    07/2002 to 06/2003
    Role: Principal Investigator

    Project Goal: Improve care for children with cancer in Texas.

  • Methotrexate-induced CNS injury in childhood leukemia.

    ONS Foundation / Sigma Theta Tau (Subcontract with University of Arizona)
    07/2001 to 06/2003
    Role: Co-PI

    Baylor subcontract award project goal: To investigate a methotrexate-induced central nervous system injury model in children with acute lymphoblastic leukemia.

  • Sleep, fatigue and exercise in children with cancer

    ONS Foundation
    07/2001 to 06/2002
    Role: co-PI

    Project Goal: To investigate relationship of sleep, fatigue, and exercise in children with cancer.

Pages

Faculty News

Duke University School of Nursing Appoints Two Preeminent Researchers to Endowed Professorships

2013-05-03
Dr. Elizabeth Merwin and Dr. Marilyn Hockenberry have been named to endowed professorships at Duke University School of Nursing due to their careers dedicated to research, scholarship, and patient...

Hockenberry Senior Author of Wong's Essentials of Pediatric Nursing Ninth Edition

2012-10-07
Elsevier has published the ninth edition of Wong's Essentials of Pediatric Nursing with Marilyn Hockenberry as senior author.

Hockenberry Publishes in Journal of Pediatric Oncology Nursing

2012-09-30
Marilyn Hockenberry published an article entitled "An outpatient urgent care bay within a pediatric cancer and hematology center" in the Journal of Pediatric Oncology Nursing.

Hockenberry Publishes in Leukemia and Lymphoma

2012-09-23
Professor Marilyn Hockenberry published an article entitled "Chemotherapy-related changes in central nervous system phospholipids and neurocognitive function in childhood acute lymphoblastic leukemia...

Hockenberry Submits NIH R01 Proposal to Study Leukemia Treatment Symptom Clusters

2012-09-09
Marilyn Hockenberry and team submitted an NIH R01 transfer application entitled "Phenotype-Genotype Associations with Symptoms During Childhood Leukemia Treatment" requesting funding for a five-year...

Hockenberry Submits Application to Study Children with Acute Lymphoblastic Leukemia Receiving Treatment with Methotrexate

2012-09-09
Marilyn Hockenberry submitted a Baylor College of Medicine subcontract. This subcontract arrangement facilitates Dr. Hockenberry’s continued work on her NIH R01 project that will continue at Baylor...

Hockenberry Submits Children’s Oncology Group Subcontract Proposal

2012-09-09
Marilyn Hockenberry submitted a Children’s Oncology Group subcontract proposal requesting funding for a seven-month period with a start date of August 1, 2012. Dr. Hockenberry will participate in the...

Hockenberry Receives Awards for Research, Writing

2011-10-03
Consulting Professor Marilyn Hockenberry was awarded the 2011 Distinguished Nurse Researcher Award and the 2011 Journal of Pediatric Oncology Nursing Writing Award at the 35th national conference of...