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Cristina C. Hendrix, DNS, GNP-BC, FNP, FAAN

Associate Professor
Chair, Clinical Health Systems & Analytics Division
(919) 684-9358
2043 Pearson Building

Dr. Hendrix completed her BSN at the University of Santo Tomás in Manila, Philippines. She earned an MSN-FNP at the University of Alabama and a DNS from Louisiana State University. She also completed a Post-Master's GNP (Gerontological Nurse Practitioner) at the Duke University School of Nursing. Dr. Hendrix’s background includes experience as a critical care nurse, followed by practicing as a family nurse practitioner. She presently practices as a Gerontological Nurse Practitioner.

Dr. Hendrix's program research focuses on developing interventions to support the family caregivers of chronically ill patients. She is presently funded by the NIH-National Institute of Nursing Research to investigate the effects of an individualized, experiential training about home care for family caregivers given before hospital discharge of their loved ones suffering from cancer. Dr. Hendrix is also a nurse investigator at the Geriatrics Research, Education, and Clinical Center at the Durham VA. She has been selected to serve on the Nursing Research Advisory Group (NRAG) of the Department of Veterans Health Affairs, Office of Nursing Services. Dr. Hendrix and her VA Transitional Care Partners team were one of the 10 recipients of the 2012 VA Office of Nursing Services Innovations Award, a national award mechanism that recognizes nursing leadership in quality improvement.

Dr. Hendrix is also a member of Sigma Theta Tau, the American Association of Nurse Practitioners, the Gerontological Society of America, and the Southern Nursing Research Society in Nursing, and is President-Elect of the Philippine Nurses Association of North Carolina.

Academic Program Affiliations

  • PhD in Nursing Program
  • Doctor of Nursing Practice Program
  • Master of Science in Nursing Program


  • DNS - Louisiana State University Health Sciences Center
  • MSN - University of Alabama- Birmingham
  • BSN - University of Santo Tomas, Manila, Philippines

Research Interests

Dr. Hendrix’ program of research deals with the older adult population. Her dissertation investigated improving ways to assess for elderly depression in institutionalized settings. During her doctoral work, Dr. Hendrix was also involved in providing for an experiential training program for Alzheimer’s caregivers.  In her present pilot, Dr. Hendrix investigates the feasibility of offering the individualized experiential training approach to enhance self-efficacy in symptom management skills of caregivers of older cancer patients. Dr. Hendrix is also a co-investigator in a study investigating the effects of interdisciplinary geriatric-based interventions on older cancer patients.

Awards and Honors

  • 2015 || Fellow, American Academy of Nursing
  • 2012 || VA Office of Nursing Services Innovations Award, U.S. Department of Veterans Affairs
  • 2009 || Best Research Poster, Gerontological Advanced Practice Nurses Association Annual Educational Conference and Business Meeting
  • 2009 || Nurse Researcher of the Year, Philippine Nurses Association of America
  • 2006 || End-of-Life Nursing Education Consortium (ELNEC) - Graduate Teaching Award Winner, American Association of Colleges of Nursing (AACN) Masters Education Conference
  • 2002 || Distinguished Graduate Award, Epsilon Nu Sigma Theta Tau International Honor Society of Nursing
  • 2002 || Dr. Linda Corson Jones Nursing Research Abstract Award, 12th Annual Nursing Research Day, Sigma Theta Tau International – Epsilon Nu Chapter
  • 2001 || FA Davis Award for Writing Excellence, LSUHSC School of Nursing
  • 2000 || Who’s Who Among Students in American Universities & Colleges
  • 1995 || Finalist – Academic Excellence Award GPA 4.0 (Graduate School), Linn-Henley International Awards at University of Alabama at Birmingham
  • 1995 || Sigma Theta Tau International Honor Society of Nursing, Beta Epsilon Chapter
  • 1991 || Sixth Place among 20,000 Examinees in the Philippine Nurses Board Examination
  • 1991 || Best in Clinical Practice (Gold Medal), University of Santo Tomas
  • 1991 || Cum Laude – Bachelor of Science in Nursing, University of Santo Tomas School of Nursing

Areas of Expertise

  • Gerontology
  • Health Disparities
  • Oncology

Areas of Interest

Informal home caregiving
Self-efficacy among caregivers and patients
Chronic illness management in the elderly
Hospital to home transition of care

Representative Publications

  • 2015 -- PubMed # : 26062925 Hendrix, C. C. and Bailey Jr, D. E. and Steinhauser, K. E. and Olsen, M. K. and Stechuchak, K. M. and Lowman, S. G. and Schwartz, A. J. and Riedel, R. F. and Keefe, F. J. and Porter, L. S. and Tulsky, J. A. Effects of enhanced caregiver training program on cancer caregiver's self-efficacy, preparedness, and psychological well-being. Support Care Cancer. June, 2015
  • 2014 -- PubMed # : 25445314 Hastings, S. N. and Betts, E. and Schmader, K. E. and Weinberger, M. and Van Houtven, C. H. and Hendrix, C. C. and Coffman, C. J. and Stechuchak, K. M. and Weiner, M. and Morris, K. and Kessler, C. and Oddone, E. Z. Discharge information and support for veterans Receiving Outpatient Care in the Emergency Department: study design and methods. Contemp Clin Trials. November, 2014 39(2); 342-50
  • 2014 -- PubMed # : 24837544 Van Houtven, C. H. and Oddone, E. Z. and Hastings, S. N. and Hendrix, C. and Olsen, M. and Neelon, B. and Lindquist, J. and Weidenbacher, H. and Boles, J. and Chapman, J. and Weinberger, M. Helping Invested Families Improve Veterans' Experiences Study (HI-FIVES): study design and methodology. Contemp Clin Trials. July, 2014 38(2); 260-9
  • 2014 -- PubMed # : 25023250 Shaw, R. J. and McDuffie, J. R. and Hendrix, C. C. and Edie, A. and Lindsey-Davis, L. and Nagi, A. and Kosinski, A. S. and Williams Jr, J. W. Effects of nurse-managed protocols in the outpatient management of adults with chronic conditions: a systematic review and meta-analysis. Ann Intern Med. July, 2014 161(2); 113-21
  • 2014 -- PubMed # : 25390367 Orto, V. and Hendrix, C. C. and Griffith, B. and Shaikewitz, S. T. Implementation of a smart pump champions program to decrease potential patient harm. J Nurs Care Qual. Apr-Jun, 2014 30(2); 138-43
  • 2013 -- PubMed # : 24048348 Shin, J. Y. and Hendrix, C. C. Management of patients with Parkinson disease. Nurse Pract. October, 2013 38(10); 34-43; quiz 44
  • 2013 -- PubMed # : 24170636 Hendrix, C. and Tepfer, S. and Forest, S. and Ziegler, K. and Fox, V. and Stein, J. and McConnell, E. S. and Hastings, S. N. and Schmader, K. and Colon-Emeric, C. Transitional Care Partners: A hospital-to-home support for older adults and their caregivers. J Am Assoc Nurse Pract. August, 2013 25(8); 407-14
  • 2013 -- Shaw, R. J. and McDuffie, J. R. and Hendrix, C. C. and Nagi, A. and Edie, A. and Lindsey-Davis, L. and Williams, J. W. Jr. A Systematic Review: Effects of Nurse-Managed Protocols in the Outpatient Management of Adults with Chronic Illness (VA-ESP Project #09-010) August, 2013
  • 2013 -- PubMed # : 21949091 Hendrix, C. C. and Landerman, R. and Abernethy, A. P. Effects of an individualized caregiver training intervention on self-efficacy of cancer caregivers. West J Nurs Res. May, 2013 35(5); 590-610
  • 2013 -- PubMed # : 23481875 Simmons, K. R. and Sinning, M. A. and Pearson, J. A. and Hendrix, C. Implementing a home-based exercise prescription for older patients with peripheral arterial disease and intermittent claudication: a quality improvement project. J Vasc Nurs. March, 2013 31(1); 2-8


Grant Funding (Selected)

  • Building International Relationship and Collaborative Work in Informal Caregiving: A Partnership between Duke University School of Nursing and University of Santo Tomas College of Nursing

    Duke School of Nursing, Office of Research Affairs (ORA)
    03/2015 to 02/2017

    Project Goal: (a) to promote research partnership between UST-College of Nursing and DUSON through collaborative endeavors such as mentoring and (b) to conduct a pilot that explores the needs of family and friends in caring for their loved ones at home during the first week of hospital discharge.

  • Enhancing AGNP and FNP Curricula to Address the Needs of Individuals with Multiple Chronic Conditions (Advanced Nursing Education Grant)

    Health Resources and Service Administration
    07/2013 to 06/2016

    Project Goal: The purpose of the proposed project is to improve the competency of Adult-Gerontological Nurse Practitioner and Family Nurse Practitioner (AGNP and FNP) students at Duke University School of Nursing (DUSON) in managing the primary care needs of adults with multiple chronic conditions (MCC), including their mental health (MH) needs.

  • Discharge Information and Support for Patients receiving Outpatient care in the Emergency Department [DISPO ED]

    VA HSR&D
    01/2013 to 06/2016
    Role: Co-investigator

    Project Goal: To examine the impact of a primary care-based nurse telephone support program for Veterans treated and released from the ED who are at high risk for repeat visits.

  • Cultural Influences on the Needs of Older Informal Cancer Caregivers

    The Reed Foundation
    09/2014 to 08/2015

    Project Goal: To explore the needs of older cancer caregivers during the hospital to home transition, and determine how these needs vary based on caregiver spirituality and relationship with the care recipient.

  • IPA - Loretta Matters

    Durham Veterans Affairs Medical Center
    02/2014 to 09/2014
  • IPA - Loretta Matters

    Durham Veterans Affairs Medical Center
    02/2013 to 09/2013
  • Training Informal Caregivers of Frail Older Veterans Before Hospital Discharge

    Veterans Affairs Health Services Research and Development (HSR&D) Pilot
    PPO 09-272-1
    03/2010 to 02/2011
    Role: PI

    Project Goal: The specific aims of the study are to (1) determine the feasibility of conducting an
    individualized, tailored training program for informal caregivers of frail older veterans prior to
    their hospital discharge and (2) determine the impact of this training program on self-efficacy
    and caregiving preparedness on informal caregivers of frail older veterans. As a secondary aim,
    data will be collected on patients’: physical symptom intensity and distress and use of
    emergency services (ED) or rehospitalization within 14 and 30 days of hospital discharge.

  • TransitionaL Care (TLC) Partners for Older Veterans at Home

    Veterans Affairs Medical Center – Geriatric Education Center
    01/2010 to 09/2012
    Role: PI

    Project Goal: The TLC program is an NP/PA-led transitional program that supports the hospital-to-home transition of older veterans who are at high risk for rehospitalization, emergency
    department visits, or institutionalization. Based on Naylor’s Transitional Care model, the TLC
    program will identify hospitalized older adults at high risk for complicated home discharge.
    Thereafter, the TLC NP/PA will conduct hospital visit prior to discharge as well as home visits
    after hospital discharge. Other TLC partners for home visit include social worker and
    occupational therapist. Through the TLC program, we aim to reduce rate of rehospitalization,
    hospital days of care, emergency department visits and institutional care of patients; and
    promote preparedness and reduce burden among informal caregivers. We also intend to
    increase patient’s and caregiver’s satisfaction towards the VA health care.

  • CONNECT for Better Falls Prevention in Community Living Centers (CLCs)

    Veterans Affairs Health Services Research & Development
    EDU 08-417
    08/2009 to 07/2012
    Role: Safety Officer

    Project Goal: This is a randomized, controlled, single-blind study testing whether facilities receiving CONNECT (educational intervention that teaches staff to improve connections within and between disciplines, improve information flow,a and seek out cognitive diversity in problem-solving) plus a falls QI educational intervention (FALLS) will result in: 1) improved fall-related process measures; and 2) decreased fall rates compared to facilities receiving FALLS alone.

  • Enhanced Self-Efficacy Training for Informal Cancer Caregivers

    National Institutes of Health
    09/2008 to 07/2013
    Role: Project Director

    Project Goal: The overall goal of this study is to examine the effects of an enhanced caregiver training protocol that not only teaches informal caregivers knowledge and skills for managing patient symptoms, but also provides strategies for managing their own psychological distress. We anticipate this training will increase caregivers’ self-efficacy and improve important caregiver outcomes (depression, anxiety, burden, quality of life) and patient outcomes (symptom distress/intensity, depression, anxiety, and quality of life). Our study will compare the effects of this protocol to an education control condition that equates for interventionist time and attention.


Friday, June 1, 2018

PhD student Yesol Yang and Cristina Hendrix recently published an article entitled "Cancer-Related Cognitive Impairment in Breast Cancer Patients: Influences of Psychological Variables" in the Asia Pacific Journal of Oncology Nursing. 


Tuesday, May 29, 2018

The Duke Elder Family/Caregiver Training (DEFT) Center was created to train, educate and empower individuals in their role as caregivers of homebound older adults.

Tuesday, May 2, 2017

A report published by the Centers for Disease Control and Prevention predicts that during the next 25 years the population of Americans who are 65 years and older will double to about 72 million. With this increase in the older adult population comes a need to raise awareness of vital aging issues through education, research, clinical practice and community or population health.

Tuesday, March 28, 2017

Cristina Hendrix was recently named the chair of the Clinical Health Systems & Analytics Division effective July 1. Hendrix joined DUSON in 2002 and is currently an associate professor with tenure. While she has been spending 50 percent of her position fulfilling a joint appointment at the Geriatric Research, Education, and Clinical Center of the Durham VA Health Sciences Center, Hendrix will transition this summer to having her position 100 percent time with DUSON.

Wednesday, March 22, 2017

Patients 60 years of age and older are often readmitted into an acute care hospital within 30 days of discharge. These readmissions can be costly for the patient and the facility. According to the Agency for Healthcare Research and Quality, nearly one in five of all hospital patients covered by Medicare are readmitted within 30 days, accounting for $15 billion a year.

Friday, November 11, 2016

DNP alumni Tamara Link publishes an article entitled "Reducing Inappropriate Antibiotic Prescribing for Adults with Acute Bronchitis in an Urgent Care Setting: A Quality Improvement Initiative" in the Advanced Emergency Nursing Journal. The article was co-authored with Cristina Hendrix and experts from Durham Veterans Affairs Medical and FastMed Urgent Care.

Friday, October 7, 2016

More than 35 women from Wake County recently joined Dean Marion E. Broome for "Conversations with Duke Nurse Practitioners Women's Health Series." The lunch discussion, held at the Preston Wood Country Club in Cary, N.C., was on "Managing Dementia from a Caregiver's Perspective." The guest speaker for the event was Cristina Hendrix.

Thursday, September 29, 2016

Cristina Hendrix was chosen to receive The Outstanding Thomasian Alumni (TOTAL) award from the University of Santo Tomas (UST) and the UST Alumni Association, Inc. The TOTAL award is the highest honor bestowed by the University in recognition of their significant and exemplary contribution to the society and the Church.

Friday, September 16, 2016

Cristina Hendrix was recently featured in an article entitled "Torres of Nursing benchmarks in Duke University." The article is about Assistant Professor Gian Carlo Torres with the University of Santo Tomas (UST) who visited DUSON weekly as part of the two-week global nursing course offered through OGACHI. Torres was mentored by Hendrix as part of the research study to build capacity among the faculty of the UST College of Nursing.

Friday, August 19, 2016

Cristina Hendrix and her team received a $1.5 million, three-year grant from the Duke Endowment to create the Duke Elder Family/Caregiver Training (DEFT) Center. The DEFT Center will offer the first academic-medical-community model for assisting caregivers following hospital discharge.

The Center will incorporate services from DUSON, the Duke University Health System and the community. Caregivers of elderly patients discharged from the hospital will receive training that covers the technical and adaptive skills needed for effective home care.