PhD Alumna Befus Publishes Article in The Journal of Alternative and Complementary Medicine

PhD Alumna Befus Publishes Article in The Journal of Alternative and Complementary Medicine

PhD alumna Deanna Befus recently published an article entitled "Management of Menopause Symptoms with Acupuncture: An Umbrella Systematic Review and Meta-Analysis" in The Journal of Alternative and Complementary Medicine. Co-authors include experts from Duke Clinical Research Institute, Duke University Medical Center Library, Durham Veterans Affairs Medical Center, Duke University Medical Center and Duke University School of Medicine. 

The article was featured in a press release entitled "Can Acupuncture Help Alleviate Menopausal Symptoms" published on libertpub.com where Befus is quoted saying she was “impressed with the notable improvements in vasomotor symptom frequency, severity, and several quality of life measurements with acupuncture compared with no acupuncture. The evidence of benefit of acupuncture for bothersome vasomotor symptoms is compelling.”

Abstract

Objectives: Vasomotor symptoms (VMSs) are the most common symptoms reported during menopause. Although hormone therapy is effective for reducing VMSs, its use is restricted in some women. Many women with VMSs thus seek nonhormonal, nonpharmacologic treatment options such as acupuncture.

Design: An umbrella systematic review (SR) was conducted, supplemented by a search of published randomized controlled trials (RCTs), that assessed the effectiveness of acupuncture for VMSs, health-related quality of life (HRQOL), and adverse effects of treatment in perimenopausal or postmenopausal women. Meta-analyses were conducted using a random-effects model when data were sufficient.

Results: Three SRs and four new RCTs were identified that met eligibility criteria. Meta-analyses of this study revealed statistically significant standardized mean differences (SMDs) associated with acupuncture compared with no acupuncture at reducing VMS frequency (SMD -0.66, 95% confidence interval [CI] -1.06 to -0.26, I2 = 61.7%, 5 trials) and VMS severity (SMD -0.49, 95% CI -0.85 to -0.13, I2 = 18.1%, 4 trials) and improving HRQOL outcomes (SMD -0.93, 95% CI -1.20 to -0.67, I2 = 0.0%, 3 trials). SMDs were smaller or not statistically significant when acupuncture was compared with sham acupuncture.

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